I'm often surprised how few people realize that there are some quality comics on the web that aren't syndicated in newspapers. Here's a list of my top 3. Happy Friday!
http://www.penny-arcade.com/comic for general gaming and industry humor.
http://www.somethingpositive.net For the dry, sarcastic, person inside you. More of a sitcom style comic.
http://www.lfgcomic.com A new comic, I'm really enjoying it. Takes the standard fantasy MMORPG game stereotypes in a fun way. I hope this one succeeds in staying around.
Followup: Do you have favorite web comics? Post and discuss.